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Highlights in This Issue


Image of change in asthma control questionnaire scores in the 2 study groups

Original Contribution

Lansoprazole for Children With Poorly Controlled Asthma: A Randomized Clinical Trial

To test the effect of treating asymptomatic gastroesophageal reflux (GER) on children with asthma, investigators randomized 306 children without GER to receive lansoprazole or placebo. In an editorial, Martinez discusses perils of therapeutic creep.

Image of cumulative survival by BRCA1/2 status

Original Contribution

Association Between BRCA1 and BRCA2 Mutations and Survival in Women With Invasive Epithelial Ovarian Cancer

In an analysis of pooled data from 26 studies, Bolton and colleagues compared survival among 3879 women with and without the BRCA1/2 gene who had invasive epithelial ovarian cancer. In an editorial, Hyman and Spriggs discuss implications of these findings.

Image of association between serum concentration of perfluooroctane sulfonic acid at age 5 y and antidiphtheria antibody concentration at age 7 y

Original Contribution

Serum Vaccine Antibody Concentrations in Children Exposed to Perfluorinated Compounds

Grandjean and colleagues assessed the effect of perfluorinated compounds (PFCs), which are present in food packaging, on diphtheria and tetanus immunizations in a cohort of 656 Faroe Island children.

Clinician's Corner | Grand Rounds

Caregiving Burden, Stress, and Health Effects Among Family Caregivers of Adult Cancer Patients

Bevans and Sternberg discuss stresses associated with caregiving required by family members and friends in the presentation of a 53-year-old woman shouldering the care of her husband while he underwent hematopoietic stem cell transplantation for acute myelogenous leukemia.

A Piece of My Mind

Of What Am I Afraid?

"Marriage, divorce, coming out—none of these things are as life altering as gender change."

Image of papules, plaques, and subcutaneous nodules on patient's left wrist

Clinical Challenge

Cutaneous Granuloma

An 85-year-old man, receiving oral methylprednisolone therapy for Sjögren syndrome, had a 5-month history of papules, plaques, and subcutaneous nodules on his face, trunk, and extremities that had not responded to topical therapies. What would you do next?

Image of growth chart for Ms K, a 14-year-old girl with BMI of 40

Readers Respond

A 14-Year-Old Struggling to Lose Weight

Ms K is a 14-year-old girl with a BMI of 40 and who has conflicts with her family over food choices. How would you manage her clinical care?

Image of child using asthma medication inhaler

Patient Page

Childhood Asthma

For your patients: Information about childhood asthma. Past JAMA Patient Pages are also freely available in English and Spanish.

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JAMA Media Coverage

View the JAMA Report Video: Lansoprazole for Children With Poorly Controlled Asthma: A Randomized Clinical Trial

Prevalence of Oral HPV Infection in the United States, 2009-2010, by Gillison et al.

New York Times

USA Today

ABC News

CBS News

San Francisco Chronicle


Serum Vaccine Antibody Concentrations in Children Exposed to Perfluorinated Compounds, by Grandjean et al.

USA Today

NPR

ABC News

PBS NewsHour

CBS News


Read more media coverage here.

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