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  Vol. 279 No. 15, April 15, 1998 TABLE OF CONTENTS
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Vitamin E and Prostate Cancer

Joan Stephenson, PhD

JAMA. 1998;279:1153.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Moderate, daily doses of vitamin E sharply reduced the risk of prostate cancer in male smokers and also lowered their chances of dying from the disease, according to the latest results from a large prevention trial conducted by the National Cancer Institute (NCI) and the National Public Health Institute of Finland (J Natl Cancer Inst. 1998;90:440-446).

In the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (ATBC Study), 29133 Finnish male smokers 50-69 years of age were randomly assigned to receive a 50-mg daily dose of vitamin E (as {alpha}-tocopherol), a 20-mg daily dose of beta carotene, both supplements, or a placebo. The latest analysis of the study's findings found that the men who received the daily dose of 50 mg of vitamin E—about 3 times the recommended daily allowance—for 5 to 8 years (and a median of 6.1 years) had one third fewer prostate cancer diagnoses and . . . [Full Text of this Article]



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