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Bone Mineral Density and High-Trauma Fractures
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To the Editor: We have comments regarding the study of high-trauma fractures and low bone mineral density in older women and men by Ms Mackey and colleagues.1 First, it appears that the majority of high-trauma fractures described were due to rather minimal trauma, given that 37.7% of patients in the Study of Osteoporotic Fractures (SOF) cohort and 51.1% in the Osteoporotic Fractures in Men Study (MrOS) cohort sustained fracture due to a fall from more than standing height. This could have contributed to the positive association of osteoporosis with high trauma.
It would be helpful to know whether any persons sustained a low-trauma fracture after a high-trauma fracture or vice versa. This would give more information about underlying osteoporosis, rather than the intensity of trauma, as a cause of increased risk of fracture. Also, fracture at any site would increase the predisposition to further fracture by other mechanisms such as . . . [Full Text of this Article]
Hari Kumar K. V. S., MD
hariendo@rediffmail.com
Abhyuday Verma, MD
Department of Endocrinology
Medwin Hospitals
Nampally, Hyderabad, India
RELATED ARTICLE
High-Trauma Fractures and Low Bone Mineral Density in Older Women and Men
Dawn C. Mackey, Li-Yung Lui, Peggy M. Cawthon, Douglas C. Bauer, Michael C. Nevitt, Jane A. Cauley, Teresa A. Hillier, Cora E. Lewis, Elizabeth Barrett-Connor, Steven R. Cummings, and for the Study of Osteoporotic Fractures (SOF) and Osteoporotic Fractures in Men Study (MrOS) Research Groups
JAMA. 2007;298(20):2381-2388.
ABSTRACT
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RELATED LETTER
Bone Mineral Density and High-Trauma Fractures—Reply
Dawn C. Mackey and Steven R. Cummings
JAMA. 2008;299(13):1543.
EXTRACT
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