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Bone Mineral Density and High-Trauma Fractures—Reply
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In Reply: In response to Drs Kumar and Verma, our results indicate that the force applied to the bone during a fracture cannot be judged by conventional low- and high-trauma classifications, such as falls from standing height. Therefore, such classifications are not useful for determining whether a fracture is related to bone mineral density or future fracture risk.
Very few men sustained subsequent fracture during follow-up in the MrOS. Among the 8022 women in the SOF, 1082 sustained a subsequent fracture following a first-incident low-trauma fracture, and 96 sustained a subsequent fracture following a first-incident high-trauma fracture. Of those who sustained a subsequent fracture following a first-incident low-trauma fracture, 1025 (95%) had low-trauma and 57 (5%) had high-trauma subsequent fractures. Similarly, among SOF women who sustained a subsequent fracture following a first-incident high-trauma fracture, 91 (95%) had low-trauma and 5 (5%) had high-trauma subsequent fractures. However, because the intensity of . . . [Full Text of this Article]
Dawn C. Mackey, MSc
dmackey@sfcc-cpmc.net
Steven R. Cummings, MD
San Francisco Coordinating Center
California Pacific Medical Center Research Institute
San Francisco
RELATED ARTICLE
High-Trauma Fractures and Low Bone Mineral Density in Older Women and Men
Dawn C. Mackey, Li-Yung Lui, Peggy M. Cawthon, Douglas C. Bauer, Michael C. Nevitt, Jane A. Cauley, Teresa A. Hillier, Cora E. Lewis, Elizabeth Barrett-Connor, Steven R. Cummings, and for the Study of Osteoporotic Fractures (SOF) and Osteoporotic Fractures in Men Study (MrOS) Research Groups
JAMA. 2007;298(20):2381-2388.
ABSTRACT
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RELATED LETTER
Bone Mineral Density and High-Trauma Fractures
Hari Kumar K. V. S. and Abhyuday Verma
JAMA. 2008;299(13):1542-1543.
EXTRACT
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