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Stem Cells and Their Potential for Clinical Application
Edited by N. M. Bilko, B. Fehse, W. Ostertag, and C. Stocking
282 pp, $179.95
Dordrecht, the Netherlands, Springer, 2007
ISBN-13: 978-1-4020-6467-8
JAMA. 2008;299(14):1724-1725.
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This book represents the proceedings from a North Atlantic Treaty Organization–sponsored workshop on stem cells. The workshop was held in Kiev and Simeiz in the Ukraine in August 2006 and included participants presenting their stem cell research from Western and Eastern Europe, Russia, the United States, and Canada. The book is neatly divided into sections on hematopoietic stem cells and hematopoiesis; biology of nonhematopoietic stem cells; stem cells and malignancy; stem cell processing, expansion, and genetic modification; and clinical transplantation.
Most of the topics deal with basic science experimentation, although the amount of data actually presented is variable by chapter. Moreover, the book is short on figures and legends, making it difficult to read and to retain new concepts. Nevertheless, some of the chapters are excellent, such as those on RUNX1 transcription factor as a gateway to acute leukemia (from Lund University Hospital in Sweden) and that on osteopetrosis models . . . [Full Text of this Article]
Paulette Mehta, MD, Reviewer
Hematology/Oncology
Departments of Pediatrics and Internal Medicine
University of Arkansas
Little Rock
paulette.mehta@gmail.com
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