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Endothelial Biomedicine
Edited by William C. Aird
1856 pp, $285
New York, NY, Cambridge University Press, 2007
ISBN-13: 978-0-5218-5376-7
JAMA. 2008;299(19):2328.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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The endothelium is a highly complex, integrated system that lines the body's blood vessels, separating the intravascular and extravascular spaces into compartments and regulating transport between them. In many disease states, endothelial damage contributes substantially to clinical pathophysiology.
To describe Endothelial Biomedicine as a comprehensive textbook on the function of the endothelium in health and its dysfunction in disease may understate the value of this remarkable text. In this first-ever systematic integration of what has been learned about the endothelium as it relates to the traditional medical disciplines, the editor establishes endothelial biomedicine as an entity unto itself—providing it with a history, setting forth a body of knowledge, establishing a research agenda, and conveying how education in the field should proceed.
The text is divided into 5 parts: "Context," "Endothelial Cell as Input-Output Device," "Vascular Bed/Organ Structure in Health and Disease," "Diagnosis and Treatment," and "Challenges and Opportunities." The initial . . . [Full Text of this Article]
Michael Domanski, MD, Reviewer
Atherothrombosis and Coronary Artery Disease Branch
National Heart, Lung, and Blood Institute
Bethesda, Maryland
domanskm@nhlbi.nih.gov
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