This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Topic Collections  • Viral Infections  • Neurology  • Neuromuscular diseases  • Immunization  • World Health  • Drug Therapy  • Adverse Effects  • Infectious Diseases  • Alert me on articles by topic  Social Bookmarking   What's this?

Joan Stephenson, PhD

JAMA. 2009;302(11):1161.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Sparked by concerns about a surge of poliomyelitis cases in Nigeria caused by a vaccine-derived strain of type 2 poliovirus, health officials stepped up efforts to curb its spread, according to the Global Polio Vaccine Initiative (http://www.polioeradication.org/content/general/current_monthly_sitrep.asp).

Although type 2 wild poliovirus (1 of the 3 serotypes of wild poliovirus) had been eradicated in 1999, it reemerged a few years ago when weakened type 2 virus in oral polio vaccine mutated. For reasons not well understood, circulating vaccine-derived poliovirus began spreading more aggressively in 2009. By late July, 124 cases of paralysis caused by vaccine-derived virus had been confirmed for 2009, more than 4 times the number of cases confirmed in July 2008.

Nigeria held nationwide immunization days in early August using trivalent oral polio vaccine in order to tackle both the vaccine-derived type 2 virus and an increase in type 3 cases. However, violence . . . [Full Text of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?