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Bridget M. Kuehn

JAMA. 2009;302(4):375.

	Since this article does not have an abstract, we have provided the first 145 words of the full text and any section headings.

The National Institutes of Health (NIH) is funding a large prospective study that may shed light on genetic and environmental factors that contribute to autism spectrum disorders, as well as identify early biological signs of autism (http://www.earlistudy.org/).

The Early Autism Risk Longitudinal Investigation (EARLI) will enroll as many as 1200 mothers of children with autism from the start of a subsequent pregnancy and then monitor the resulting children until the age of 3 years. The women will be asked to complete surveys and provide biological samples; such samples also will be collected from the children, who will undergo periodic assessments for autism.

Several institutions in Pennsylvania, California, and Maryland will participate. A $14 million grant from the NIH and a $2.5 million grant from Autism Speaks, an advocacy group for children with autism and their families, are funding the study.

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