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To the Editor: In their randomized controlled trial, Dr Morey and colleagues¹ reported that among older, long-term (5 years) survivors of colorectal, breast, and prostate cancer, a diet and exercise intervention reduced the rate of self-reported functional decline. The body mass index (BMI) of the participants ranged from 25 to 40 (calculated as weight in kilograms divided by height in meters squared).

Approximately 41% of men and 53% of women in the United States have levels of serum 25-hydroxyvitamin D below 28 ng/mL.² An indicator of vitamin D status, serum 25-hydroxyvitamin D may be low in obese adults and has an inverse relationship with BMI.³ Epidemiologic studies indicate that low levels of serum 25-hydroxyvitamin D are associated with an increased risk of colon, prostate, and breast cancer, along with higher mortality from these cancers.⁴ Evidence also suggests that in older persons a mean serum concentration greater than 65 nmol/L . . . [Full Text of this Article]

Asit B. Shil, MD
shil@usc.edu

Maureen P. Strohm, MD; Chris Feifer, DrPH
Keck School of Medicine
University of Southern California
Los Angeles

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