This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

James D. Cherry, MD

JAMA. 1990;263(12):1679-1680.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The article by Griffin et al¹ in this issue of THE JOURNAL is the third recent controlled study that has examined the risk of seizures and other acute neurological illnesses after immunization with pertussis-containing vaccines.^1-3 In these three studies, which involved about 230 000 children and 713 000 immunizations, no evidence of a causal relationship between pertussis vaccine and permanent neurological illness was found. In the two previously published studies, an association between immunization and first febrile seizures was noted; Walker and associates² found that the incidence of febrile seizures in the immediate postimmunization period was 3.7 times that in the period 30 days or more after immunization. Shields and colleagues³ estimated about one febrile seizure for every 1000 children 10 months of age or older who were immunized.

In addition to the three recent studies mentioned above, which fail to show a causal relationship between . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Pediatrics, UCLA School of Medicine, Los Angeles, Calif.

Footnotes
Reprint requests to Division of Infectious Diseases, Department of Pediatrics, UCLA School of Medicine, Los Angeles, CA 90024 (Dr Cherry).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?