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A Perspective

John A. Pierce, MD; Burton E. Sobel, MD

JAMA. 1991;266(14):1990-1992.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

TWO BRILLIANT advances in surgery summarized in this issue of THE JOURNAL^1,2 elucidate fundamental phenomena in the pathophysiology of end-stage pulmonary disease and atrial fibrillation.

Lung Transplantation

The positive experience with lung transplantation summarized by Trulock and associates¹ is a consequence of a remarkable sequence of developments in immunology and surgery. In their series of consecutive patients with end-stage pulmonary disease, the survival rate is impressive, and the functional recovery is dramatic, with improved expiratory airflow and reduction to normal pulmonary artery pressures in those operated on for pulmonary hypertension. A majority of the patients returned to rather active lives following transplantation, in great contrast to their pretransplantation status. . . . [Full Text PDF of this Article]

Author Affiliations
From the Respiratory and Critical Care (Dr Pierce) and Cardiovascular (Dr Sobel) Divisions, Department of Internal Medicine, Washington University School of Medicine, St Louis, Mo.

Footnotes
Reprint requests to Respiratory and Critical Care Division, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110 (Dr Pierce).

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